In Summary
DeSci is emerging as a potential trend in 2025. With a current market capitalization of only $1.2 billion (0.035% of the crypto market), DeSci has much room for growth.
Notable projects driving DeSci forward include Molecule, VitaDAO, and ResearchHub, which are collectively innovating in decentralized research, data security, and funding.
Ethereum hosted 49% of projects from the previous cycle, while Solana’s market share is accelerating with 40% of new projects launching after 2023.
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Bio Protocol (BIO) serves as Binance’s first shot to spark investor expectations in a potentially fertile new area for the 2025 market: Decentralized Science, or DeSci. With most projects currently having small market caps and limited scale, what opportunities can this sector offer investors?
Below is BeInCrypto’s summary of the current DeSci landscape, based on the latest forecasts and data.
Overview of DeSci as of Early 2025
Recent reports from Messari indicate that the DeSci space remains modest yet promising in 2025. Specifically, the market capitalization of DeSci, excluding meme coins, is $1.2 billion, representing only 0.035% of the total crypto market cap.
In this emerging field, Ethereum’s blockchain hosts 49% of the projects launched in the previous cycle. Solana is gaining market share, currently accounting for 40% of projects launched after 2023.
The DeSci ecosystem map above reveals numerous projects that are several years old but have yet to gain significant traction. A recent report by BeInCrypto identified 3 signs predicting a surge in investor interest in this sector in the new year, 2025.
“The Rise of the PHDegens” – Messari predicts.
CoinMarketCap (owned by Binance) has launched a dedicated statistics page for DeSci. According to it, the sector’s market cap is currently less than $1 billion, but its trading volume exceeds $220 million. The high volume-to-market-cap ratio reflects the demand for trading DeSci tokens
Messari’s statistics also show that in the TOP 10 DeSci projects by market capitalization, 50% of the projects were launched in the past year, and 50% of the projects have experienced significant market cap growth. Some notable names include OriginTrail, VitaDAO, ResearchHub, Urolithin A, and Hippocrat.
See also: TOP 5 Low Cap Decentralized Science (DeSci) Projects to Watch
Will DeSci Explode in 2025? Which Projects Show Promise?
With a still small market capitalization, attention from investment funds, and the potential to meet real-world needs, many industry experts predict DeSci will take off in 2025.
“There will be no ‘season’ for DePIN, DeSci, and DeAI next year. They will dominate the whole of 2025,” predicts Simon, CEO of MoonRock Capital.
A recent report from the OKX exchange predicts DeSci’s potential not only in terms of investment but also in its ability to transform and accelerate scientific development globally.
“The rise of DeSci is pushing scientific research from closed to open, from centralized to democratized. DeSci’s transparent mechanisms, efficient collaboration, and data-sharing models will have a profound impact on global scientific innovation,” OKX states.
In its report, OKX also names 5 promising DeSci projects:
- Molecule: This project has allocated $2 million to support several biomedical research projects, with its ecosystem’s TVL reaching $30 million and continuing to grow.
- AminoChain: This project, having passed a $5 million funding round, has developed a decentralized biospecimen marketplace, helping patients control ownership of and benefit from their data.
- GenomesDAO: This project utilizes a decentralized genomic database to provide solutions for personalized medicine and data security.
- ResearchHub: This project has completed 2,800 peer reviews using token rewards, reducing average processing time to 9 days—far exceeding the 70-98 days of traditional scientific journals—and significantly improving transparency and efficiency in research.
- VitaDAO: This project uses governance tokens to enable community-led research funding, reducing intermediaries and minimizing financial waste.
These projects span various areas such as funding distribution and intellectual property management, healthcare data, scientific publishing, and more. Together, they are pioneering valuable new solutions with the potential to attract the attention of investors and scientists to DeSci.
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